Pakistan hammered England by nine wickets in their tour-ending Twenty20 international at Old Trafford on Wednesday.
Pakistan chase down 303 in the final ODI in Cardiff to deny England a whitewash.
Ben Stokes and Jonny Bairstow both made fifties as England beat Pakistan by four wickets in the fourth one-day international at Headingley on Thursday.
Pakistan Thursday announced a 13-man squad for the only Twenty20 against England to be played at Old Trafford on Wednesday.
Ben Stokes has returned to the England Twenty20 squad for the first time since being hit for four sixes in the final over of the World T20, when West Indies beat England.
England post the highest ever one-day international total as they beat Pakistan by 169 runs to secure a series victory at Trent Bridge.
Host posted the highest ever one-day international total and Alex Hales struck a record 171 in the third ODI against Pakistan at Trent Bridge.
Pakistan opening batsman Mohammad Hafeez has been ruled out of the remaining three one-day internationals and one-off Twenty20 against England due to calf injury.
England produce another polished display to beat Pakistan at Lord's by four wickets and take a 2-0 lead in the one-day series.
England coast to a 44-run win over Pakistan in a rain-affected first one-day international in Southampton on Wednesday.