India finished first day on 297 for 5 after Windies dent early blow.
Virat Kohli scores 43rd ODI century helps India clinch 2-0 series win against Windies.
Lewis, Pooran flickered briefly for West Indies, but a flurry of wickets in the middle overs derailed the hosts.
Off-spinner Rahkeem Cornwall could make his long-awaited Test debut, starting with the opening match August 22-26 in Antigua.
The first contest of the three-match rubber between India and West Indies has been called off due to continuous rains on Thursday.
Deepak Chahar, Rishabh Pant and Virat KOhli shine as India complete Windies whitewash.
India beat West Indies by 22 runs (D/L method) in the second T20I in Lauderhill, Florida on Sunday.
India beat West Indies by 4 wickets in the first T20I in Lauderhill on Saturday, lead 1-0.
West Indies have also recalled left-hand opening batsman John Campbell and all-rounders Roston Chase.
Chris Gayle unavailable for Carlos Brathwaite-led West Indies squad for first two T20Is.